HAVE to? No. You could run your gain considerably lower and get away with it. With that being said, you'll be much happier for now at 2 ohms. You won't have to worry about much. What people don't understand is this: when your resistance falls by half, the amount of current drawn if the voltage stays the same is doubled. The limiting factor here is how much current can safely be drawn through the output transistors. At 2200 watts at 1 ohm you're looking at 47 volts x 47 amps. So, I'd say at most 55 amps is the limit that the amplifier can draw for any amount of time and survive. Transistors have a tolerance, and it should be about 15%. To get that same 2200 watts at .5 ohm, you're going to set your gain at 33 volts. This will cause a current draw of 66 amperes. That is WELL over tolerance and that is RMS. We know that the impedence can drop to 1/4 of what it is wired to nominal. That's .125 ohms. Let's do the math there. 16v x 132 amps. Yeah... the transistors won't last long like this.
It is very important to know also, that amplifiers we run today may be greater than 80% efficient at 4 ohms, but at 1 ohm they are around 70% efficient. When you drop them to .5 ohm, they are much less efficient. If your voltage drops at all, you are even less efficient still.
It's not a recipe for success.
Edit: If you want to know how to set your gain so the amp will survive at .5 ohms, set your gain at 23.5v. This will cause a current draw of 47 amps at .5 ohm and produce 1104.5w. Remember, current is the limiting factor on those transistors.