I hope you don't use screws to hold your enclosures together (as in, if you take the screws out, the enclosure will fall apart). That's just poor craftsmanship there.
Phil at
http://www.woodlawncabinetry.com did a test using a compressor and measured at what pressure enclosures failed. If I remember correctly, he used multiple enclosures that he built and tested for their breaking points. I'm pretty sure that he found the weakest link of the enclosures to be the MDF and not the glue joint.
I took an old enclosure and pulled out every single screw from it and tried to break it. After playing it very hard and dropping it off my roof, it was still solid. I went at it with a bat and when the enclosure broke, it separated from the wood and not the joint. The sad part is that I used plumbers caulk to glue the enclosure together because it was just a ghetto quick-fix box and that's all I had.
Like I said before, you won't notice a difference and you probably won't have a failure but you are wasting screws and your time (even though it's very little) on something that is only making things worse. But either way, you won't believe me and will go on doing what you're doing. If you haven't had any trouble, why change, right?