Trunk position matter for a sealed box?

[Mechorganic 10+ year member]

Ive read a lot that for SPL the ideal positioning in the trunk is for the subs behind passenger, port behind driver. Does it matter for a SQ system and a sealed box? Im only putting 1 10" and trying to figure out which way to face it and which side itll go on, so i can get my box properly designed.

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