Firstly, I hope that you are planning on keeping the speakers all in separate chambers.- especially if you are going to be running dual amps. Two amps powering subs in 1 enclosure will likely produce quite a bit of cancelation unless you have equal power and the gains set exactly the same on both amps.
As A general rule- a ported enclosure will give you approximately 3db more output that a sealed encloure in most applications. However, some of the tight- punch of SQ will be lost and more lower "boomy" response obtained. On the other hand.----> 2 subs in a sealed enclosure in the right location can also produce an extra 3db of output and retain thier accuracy and SQ, and still hit hard.
Kinda a personal choice- your ears should make the ultimate decision.
take it easy,
-zane