Thanks for replies! Let me deal with them in order.
1. Yes, I run them from aftermarket HU, Pioneer 3800. I believe it has sufficient power and I don't listen at high volume.
2. I tried all combinations of HPF on front (and tweeters - thats how Toyota speakers are wired) and LPF on subwoofer, sometimes on and sometimes off. I wanted clarity in vocals and crystal clear highs, with emphasided bass. I believe that Focal tweeters (aluminium) were good for highs but vocal were a bit dim. With Pioneer TS 736-2, which are like more full small speakers, rather than just tweeters, I get strong mids, which probably overpower Focal midbass woofers.
3. At the end, since subwoofer has a hardware crossover at 90, I turned off software LPF on the HU. I turned on HPF on doors speakers at 80.
4. EQ was very important. I turned down midsection and made it more like V eq preset, with mids down and bass and highs up. In Pioneer, this is Powerful present eq. I think it sounds the best now. I decided to keep Pioneer tweeters so far. Pioneer has even better tweeters but they are expensive (300 dollars). So I keep 150 dollar Pioneer tweeters TS-736-2.
With this EQ adjustment, sound is quite good, especially male voices. Female are not as good but OK in general. I get good bass and good highs.
Hope this helps.