Find a good position. Make sure you are comfortable and can relax. Be sure you can clean up if a problem is to occur. Make sure you or your partner have good access to your anus.
Lubricate your anus. You might want syour partner to massage some lubricant inside your anus and rectum. This will help when the nozzle is inserted. You will want your anus to admit the nozzle so that you can relax.
As the nozzle is inserted, relax as it passes your sphincter. You might want to take a couple of deep breaths as it passes.
Relax, as your partner turns on the flow. Mentally picture yourself receiving it. A good partner will slow the flow if you experience any gripping. You may end up making a mess if you panic. Instead, try to relax, everything will be fine. If cramps come (and they probably will during your first enema) have your partner stop the flow, breath deep, and try massaging your stomach area.
If you feel the need to evacuate, ask your partner to stop the flow. Relax, the desire will pass as your colon relaxes.
You might feel your stomach expanding. Let it. Try to hold the enema for a few minutes.
When it is time to evacuate, take yourself (with the tube still in place) to the lavatory. Wait until you are in a position to evacuate before you remove the tube.
After you evacuate, take a deep breath and feel your lightness.