Nitric Oxide products have been around quite a while. BSN basically took viagra, tamed it down a bit, added some sugar, put it in a red bottle and told ronnie coleman to hold it and smile. The worst side you will experience with NO product is a minor headache. And most vitamins and nutritional supplements arent approved by the FDA either. Im not trying to be a dick and argue with you, and to be honest most supplements like creatine and NO is very worthless as far as actual muscle building goes and companies like BSN, Muscletech, VPX etc put out crappy products(at least the new stuff is) and hype it up to be great so high school kids go into their local GNC and spend hundreds of dollars on it. lol very similar to how the car audio industry works.