I'm running two Optima yellows and am having similar issues. Once my Optimas drained, from not driving the truck for two weeks, I can't get them to hold a charge for shit. I've had them both out and fully recharged (2 amp over DAYS...) by the local dealer, and they still won't last for more than a day or so.
I do have a small drain that I can't quite figure out yet, but it's only around 1.5 amps. I've never had any issues with this loss, I didn't even know it existed until the battery drained over such a long period of time and i previously have been up to 5 days without driving the truck. WTF???