The Polks will have 6.5" and 5.25" components as well as 6x9 coax. If your door takes 6x9's then get a a sheet of .5" MDF and use a jig saw to cut an oval that will the cut out. That's what I ended up doing cause I wasn't shelling out for new speakers. Components will have a big impact on how the system sounds if you have the time to install the tweeters.
As far the amps go, do you care if they're matching or not? If not, I would do some research around. The problem is you're going to get half the people that says x budget amp works great and half that say it might make power, but the sound quality isn't going to be there *shrug* I've used 50 dollar amps before that worked fine for the application. That being said, you're asking for a good chunk of power for those subs, so you'll want a decent quality amp. For the SD 8's a GTO EZ1000 is less than 200 and it's a solid amp. Anything more powerful I would shell out for the NVX. Keep in mind that several companies rebrand the same amp. The Polk pa1000.1 d and the NVX 1200.1 are the exact same board. I believe two other companies use it as well, so find a good deal. As far as being budget minded, hifonics Brutus amps make rated power for a good price. That'll be you're best budget option most likely.
For your mids and highs amp I would suggest a four channel for those Polks. I would run the tweeters hooked up to the passive crossover on one set of channels and the mids with an active crossover on the on the other set. I set my highpass around 70 to 80, safe bet is 80, and let it run full range up. It really helped with the imaging and warmth in my system. A ton. The Polk tweeters are a bit sharp for my ears, but very detailed. If you're struggling with the sound still being bright, you can do two other little tricks to soften the tweeters with out turning them down. The first is to reverse the polarity on one so it's out of phase with the other. Just the tweeters. Sounds crazy, but it helped cut out the peaks and sibilance I was getting with out sacrificing any of the details. It also helped center the sound right in front of my steering wheel instead coming from the corner where the tweeter was. And if you have time, build a tweeter sphere and mount them 3 inches off the a pillar or dash some where. It'll help reduce reflections and open up the sound.
Plus, if your tweeters are on their own channel set, you can wire in a remote gain knob into the RCA's for them and really be able to dial in the sound for each song.
Just food for thought