Here's my experience, take it for what it's worth.
Built a sealed Tempest running off a PG amp with 500 watts. Sounded very good in my car. Excelon HU with 4.5v pre-outs.
Put it in the GF's car and the bass was GONE. Pioneer HU with 2v pre-outs. Turned the gain up all the way, still not much bass. Also noticed the Polk coax's didn't sound very good and they're amped.
Long story short, her HU has 3 levels of loudness and I had to use the MID one to get back the missing bass and make the speakers sound full and loud.
There seems to be more to it than "just match the amp gain to the pre-out", at least in this case there was as everything sounded like crap compared to running off of my HU.