no.
unless... you have one sub inverted and one normal sharing a common chamber.
it won't hurt anything if you are running a single sub setup.
no it'll be out of phase with the other sub, unless you're talking about a single sub setup, in that case, the difference is going to be unnoticeable to almost anyone who listens......but you can wire a single sub inverse, it won't hurt anything, but you probably won't get a noticeable gainif you dont wire it backwards it's going to be out of phase with your components...