If it's someone who uses a PC regularly and uses even a FEW apps, getting help removing spyware/viruses is MUCH easier than remembering everything to back up, remembering all of your specific program settings, knowing HOW to go through the reformat process, having fun with drivers (chances are the CD's are LONG gone), and all that fun stuff.
I told him what to do and to post back his hijack this log. He should be pretty close to clean by now. From the looks of his log, his infection is mediocre at best and slowness is due to something else.