The question was, is it worth it? I'd say no it is not worth it for the op. Is it better, yes it is better.
To op just needs to decide for himself, BT versus better audio features and power from the HU's amp speaker output.
Which one is it going to be? A lot of good info was shared here already, while others keep debating about the voltage. If you put a silent track and play it with the gains set with a DDM for both 2 and 4 volts you will get slight less hiss with the 4 volts and other marginal benefits with the volume. I just did a listening test. I have an HU with 5 volts RCA s, old school noisy JBL multichannel amp, no noise in between tracks at all, Gains set with DDM, my volume at 15-18 with music is about all I can handle, and it goes to 50. I Put it on aux, no input turn it up to 40 before I hear noticeable audible noise, at max I hear hiss but it does not bother me or makes me turn it down.
Now for cars with external road noise, wind, outside noise etc, I'd say again it's not worth it but it is better. Will the noise be the same with a 2.5 volt RCA's? Maybe, maybe not? is it worth it? I know my volume would need to be at 35 plus instead of 12-14