Phase is the flow of energy from positive to negative. Usually we say a speaker is in or out of phase . When someone says a speaker is "out of phase" (or phase "reversed"), that usually means the positive of the amplifer output is connected to the negative lead on the speaker, and the negative output of the amplifier is connected to the positive lead on the speaker.When a normal audio signal comes thru, such as a kick drum sound, it makes the speaker pull inward first, instead of outward. If another speaker is wired correclty next to phase reversed speaker, especially a bass sounds, they can actually cancel the sound of each speaker, and you will hear almost no sound. If you unplug one the bass magically reappears. If they both move in the same direction, they will produce double the output, but if one moves opposite the other, you get nothing.
There is also a negative and postive power input on the amp, if you get that backward you will probably get smoke.
You could also wire the audio inputs into the amplifer out of phase, if you built your own cables and reversed the +/-, but if they are factory made cables this is not possible.