It depends, thc is a drug like all the others. Everyone will respond differently their first time. The thing about thc is is is a stimulate, depressent, and a hollucingen. Long term studies have shown very minor side effects, while the benefits can be extreme. Like alot of similar drugs you have to ease yourself into using it or u may have negative results. But for the goverment to class it as a c1 and say it has no medicinal value is obsurd. The fact that every day I listen to commercials about these drugs that will help with bs problems, but may cause heart problems, kidney, strokes, and the list goes on. But a drug that has shown very little harm if NOT SMOKED, but can help an uncountable number of people, if only so they can somewhat "enjoy" the last bit of time they have on this planet has no value in medicine WTF? Now lets look at alcohol, How many people die a year because of it? I am assuming you are talking for recreation. The thing about thc is if you over do it, you most likely will not even make it to your car. So if I had to suggest one I would say thc!