Im running dual 2/0 wires, its like trying to fit two small garden hoses behind my interior panels. //content.invisioncic.com/y282845/emoticons/crap.gif.7f4dd41e3e9b23fbd170a1ee6f65cecc.gif//content.invisioncic.com/y282845/emoticons/biggrin.gif.d71a5d36fcbab170f2364c9f2e3946cb.gif Running under the truck is my only real option. Im gonna run the wire inside the frame rail, each run with its own flexible liquitight conduit, strapped together. Bulkheads through the sheetmetal.you don't have to gut the entire interior to run the wire, only the panels along one side which takes 5 minutes at most. I'd go that route as then you'll never have to worry about it....
But if you do run it under the car NO wire should be lower then the lowest part of the frame, so no chance of scraping on anything.