Hell, the temperature and humidity in the room can do that.
What?
Too much Linkwitz, man. //content.invisioncic.com/y282845/emoticons/smile.gif.1ebc41e1811405b213edfc4622c41e27.gif
It's impossible for any ranged enclosure to perform on paper for all the possible wave patterns and varying amplitudes in music. //content.invisioncic.com/y282845/emoticons/smile.gif.1ebc41e1811405b213edfc4622c41e27.gif
Besides, I'm sure there are many improvements that could be made in most listening areas that would have a greater effect than an improvement in the cabinet.
Sure, if the speaker played a particular frequency or multiple thereof, you could design a technically correct enclosure for wave reinforcement. You could even get really fancy with it.
But this is music, baby!