I have seen amps trip into protect and not run the same afterward. If it went into protect, there was a very serious problem that the amp dealt with....multiple times could have gave it brain damage, so to speak.
Other than that, unless you were running like >16 ga speaker wire, that would not cause the shutdown. I truly beleive your problems now are internal, or maybe the possibility of a ground connection. I assume all ground wires are the same size as positive wiring? Not to insult your intelligence, but it happens.