You're going to have a whole lot of power going to those speakers in a 4-channel amp that can adequately power 2 10s, so be careful with the gain on the front channels. You'll also need to set the high pass filter around 100 Hz to start. My best amp for the money in a 4-channel configuration is the Precision Power P900.4. It's been very popular for the last year and half as a compact, reliable, efficient, very powerful and good sounding amplifier. This will give you 225 W @ 2 Ohms and 450W bridged @ 4 Ohms.