sq issues

I have a Pioneer mvh-2300nex HU, Alpine X-series 120w x 4 amp w/matching components & coaxials in front. KTA-450 (bridged) 100w x 2 w/Pioneer Z-series coaxials in rear. NVX 1000.1 amp w/ DC Audio sub in ported & tuned box in a 2012 Silverado Crew Cab. I've had serious SQ issues, blown many...