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<blockquote data-quote="tRidiot" data-source="post: 5221076" data-attributes="member: 569830">Alcohol is an inhibitor of gamma-amino butyric acid (GABA), itself an inhibitory neurotransmitter in the human brain. This accounts for most of alcohol&#039;s intoxicating effects, but it also simultaneously inhibits the release of vasopressin, also known as anti-diuretic hormone, or ADH.The lack of ADH leads to excessive urination (even when consuming low volumes of liquid, as in hard-liquor shooters), with concomitant loss of electrolytes. Many of the symptoms associated with hangover (headache, fatigue, etc.) are related to dehydration and the associated electrolyte imbalances.Rehydration and replacement of electrolytes are key, as is time, which is needed to clear toxic metabolites (like lactic acid) and muscle breakdown products (creatine phosphokinase, etc.).That&#039;s the short and simple version. //content.invisioncic.com/y282845/emoticons/wink.gif.608e3ea05f1a9f98611af0861652f8fb.gif</blockquote>

[QUOTE="tRidiot, post: 5221076, member: 569830"] Alcohol is an inhibitor of gamma-amino butyric acid (GABA), itself an inhibitory neurotransmitter in the human brain. This accounts for most of alcohol's intoxicating effects, but it also simultaneously inhibits the release of vasopressin, also known as anti-diuretic hormone, or ADH. The lack of ADH leads to excessive urination (even when consuming low volumes of liquid, as in hard-liquor shooters), with concomitant loss of electrolytes. Many of the symptoms associated with hangover (headache, fatigue, etc.) are related to dehydration and the associated electrolyte imbalances. Rehydration and replacement of electrolytes are key, as is time, which is needed to clear toxic metabolites (like lactic acid) and muscle breakdown products (creatine phosphokinase, etc.). That's the short and simple version. [IMG]//content.invisioncic.com/y282845/emoticons/wink.gif.608e3ea05f1a9f98611af0861652f8fb.gif[/IMG] [/QUOTE]

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