For what its worth :
I have a 2018 F-150 non B&O. I originally wanted to keep stock radio/screen so I did:
JL Audio VXI 400/4 powering JL C2 650 coax in rear for fill and JL C3 650 2 ways up front. The VXI has TUN software for DSP.
JL Audio HD1200/1 powering JL Audio Stealthbox with (2) 12"...