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<blockquote data-quote="Canaan" data-source="post: 4154933" data-attributes="member: 566706"><p>The advil will be ok, but if you are just a hour away from the roxi, go ahead w/ it.</p><p></p><p>Acetaminophen is much harder on your liver. Especially if you have been drinking.</p><p></p><p>That said:</p><p></p><p>In cases like a drinking binge...NEVER take acetaminophen.</p><p></p><p>Alcohol (Etoh) will cause Cyp2E1 induction. Cyp2E1 plays a role in the phase2 metabolism is Etoh, but also will cause free radicals to be created if acetaminophen is present. This can and will cause necrosis in the central lobular region of your liver. A dose of acetaminophen as small as 800mg in 12hr can case significant damage in such cases.</p><p></p><p>So...Tylenol for a hangover = BAD.</p><p></p><p>*cough* Toxicology major *cough*</p></blockquote><p></p>
[QUOTE="Canaan, post: 4154933, member: 566706"] The advil will be ok, but if you are just a hour away from the roxi, go ahead w/ it. Acetaminophen is much harder on your liver. Especially if you have been drinking. That said: In cases like a drinking binge...NEVER take acetaminophen. Alcohol (Etoh) will cause Cyp2E1 induction. Cyp2E1 plays a role in the phase2 metabolism is Etoh, but also will cause free radicals to be created if acetaminophen is present. This can and will cause necrosis in the central lobular region of your liver. A dose of acetaminophen as small as 800mg in 12hr can case significant damage in such cases. So...Tylenol for a hangover = BAD. *cough* Toxicology major *cough* [/QUOTE]
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