Ok, let's see....
First of all, always go by the RMS rating of everything. If your subs are 400w RMS, then yes, go with an 800w RMS amp. If you get a two channel amp, depending on it's capabilities, you can either hook the 2 subs to their own channel, you can run them off of a single channel, or you can bridge the amp and run both that way. Bridging is simply hooking the two channels of an amp together. When this is do it turns the amp from being 2 channel stereo to 1 channel mono. Lets say you go with a 200w 2 channel amp (100w per channel). If you run a sub off each channel, you will gett 100w to each. When it is bridged you get a single channel that put out 200w.
In you case, assuming you have 4ohm single voice coil subs, I would look for an amp that is 200w per channel and is 2ohm mono stable. This means that you can bridge the amp for a mono, 2ohm load. This is done by bridging the 2 channels together for a total of a 400w mono load. By wiring the subs in parallel, you drop the impedance (ohms) by half (or close to it). Every time you cut the impedance in half, you double the amps power out put. So now you have 800w rms going to your subs (400w each) through you mono channel. Still followin'?
(You can also just buy a mono amp.)
As for adding front/rear speakers, I would go with a seperate 4 channel amp and run each speaker to a channel. You can also get a 2 channel amp and run the fronts at 2ohms on one side and the rears at 2ohms off the other. But every time you drop the impedance, you increase the distortion. As far as subs go it is not that audible of a difference, but when your talking speakers it can be a different story...but not always. (This is why most home systems are at 8ohms.)
If your only running fronts, you could run them off the same amp as the subs. But from my expierance the subs tend to take away power from the speakers. This is why I recommend seperate amps.
As for the RCA's most head units come with at least 2 sets of RCA out puts. If not, some amps come with a RCA passthrough. If you don't have either you can always use a "Y" splitter and split the RCA between the two amps.
Hope this helps out.
Good luck!//content.invisioncic.com/y282845/emoticons/smile.gif.1ebc41e1811405b213edfc4622c41e27.gif