1x 12" MB Quart Onyx Dual 4ohm (ONX304) = 400W RMS
2x 6" Pyle PLPW6D Dual 4ohm = 300W RMS (Though suspiciously, on the spec sheet it says 100W)
Alpine MRX-M100 = 600W RMS @ 4ohm, 1000W RMS @ 2ohm, 500W RMS @ 1ohm
Yes, I understand those subs are far inferior and completely outclassed by the amp, but that's sort of the point. No need to get into it.
How would I best wire them up to the amp so that each sub receives its proportionate amount of power and also allows the amp to run closest to its ideal 2ohms? Do I need to make any changes to the amount of subs?, I can take away or add an extra Pyle sub if needed. Is it even a decently good idea to run 2 different types of subs from a single mono amp?
Eventual damage to the subs is acceptable but, definitely not preferred. Eventual damage to the amp is unacceptable.
Wiring 2 different types of subs is beyond me